Grinberg Lab presentation @AAIC24

We are pleased to announce the presence of our authors at AAIC24 in Philadelphia. We look forward to sharing our recent findings, which will contribute to advancing knowledge about Alzheimer's and dementia:

27 Sat, PIA day

Atypical PIA: Single-nuclei transcriptomic identifies type-specific neuronal cell vulnerability in Amnestic and Logopenic Variant Primary Progressive Aphasia Alzheimer’s disease. Felipe Pereira.

Atypical PIA: Decoding the distinctive pathogenetic mechanisms in MCHergic neurons of the lateral hypothalamic area: insights from Alzheimer's disease phenotypes. Abhijit Satpati.

Neuromodulatory Subcortical System PIA: The VLPO analog in the human hypothalamus shows tau-driven extreme loss of sleep-regulating neurons in PSP and Alzheimer's disease: unveiling the basis of NREM sleep dysfunction in taupathies. Shima Rastegar.

 

28 Sun, Day1

Tackling selective neuronal vulnerability: Subnuclei involvement of amygdala-predominant Lewy body disease in early-onset Alzheimer’s disease. Luke Fischer.

Exploring selective neuronal vulnerability in Alzheimer’s disease -- key pathways are downregulated in vulnerable subpopulations of RORB and CDH9 excitatory neurons of the entorhinal cortex at Braak 0. Alexander Soloviev.

Association of 18F-flortaucipir PET with tau neuropathology in AD and other neurodegenerative disorders. Agathe Vrillon.

 

29 Mon, Day2

Clinical performance of plasma p-tau 217 for the identification of primary Alzheimer's disease pathology and co-pathology in sporadic FTD. Igor Prufer Araujo.

Single-nuclei transcriptomic identifies type-specific neuronal cell vulnerability in Amnestic and Logopenic Variant Primary Progressive Aphasia Alzheimer’s disease. Felipe Pereira.

D13 caspase-6-cleaved tau, a new biomarker to complement Alzheimer's disease diagnosis. Liara Rizzi.

The human master circadian clock is vulnerable to tau pathology in the early stages of Alzheimer’s: a postmortem neuropathology using spatial in-situ proteomics. Gowoon Son.

 

30 Tue, Day3

Deciphering Brain Circuit Susceptibility in human Alzheimer's disease: Unveiling the Role of Sleep and Circadian Rhythms through Spatial-Omics. Lea Grinberg.

Neuropathological Mapping of Synaptic Vesicle Protein 2A in Human Brains: Ground Truth for PET Interpretation in Neurodegenerative Diseases. Mahsa Shanaki Bavarsad.

Pathways underlying selective vulnerability to Alzheimer’s disease in aminergic brainstem nuclei. Alex Ehrenberg.

Exploring the Impact of Race, African Ancestry, and APOE4 on Sex Differences in Amyloid Pathology and Cognitive Outcomes in an Admixed Population-Based Neuropathological Sample. Maison Abu Raya.

 

31 Wed, Day4

The VLPO analog in the human hypothalamus shows tau-driven extreme loss of sleep-regulating neurons in PSP and Alzheimer's disease: unveiling the basis of NREM sleep dysfunction in taupathies. Shima Rastegar.

Exploring the Impact of Race, African Ancestry, and APOE4 on Sex Differences in Amyloid Pathology and Cognitive Outcomes in an Admixed Population-Based Neuropathological Sample. Maison Abu Raya.

 

1 Thu, Day5

Preservation amidst decline: wake-promoting histaminergic system provides a novel target to mitigate sleep/wake dysfunction in Alzheimer’s disease. Abhijit Satpati.