Publications

A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease.

Nature medicine
2025

Oh HS, Urey DY, Karlsson L, Zhu Z, Shen Y, Farinas A, Timsina J, Duggan MR, Chen J, Guldner IH, Morshed N, Yang C, Western D, Ali M, Le Guen Y, Trelle A, Herukka SK, Rauramaa T, Hiltunen M, Lipponen A, Luikku AJ, Poston KL, Mormino E, Wagner AD, Wilson EN, Channappa D, Leinonen V, Stevens B, Ehrenberg AJ, Gottesman RF, Coresh J, Walker KA, Zetterberg H, Bennett DA, Franzmeier N, Hansson O, Cruchaga C, Wyss-Coray T

Pathways underlying selective neuronal vulnerability in Alzheimer's disease: Contrasting the vulnerable locus coeruleus to the resilient substantia nigra.

Alzheimer's & dementia : the journal of the Alzheimer's Association
2025

Ehrenberg AJ, Sant C, Pereira FL, Li SH, Buxton J, Langlois S, Trinidad M, Oh I, Leite REP, Rodriguez RD, Paes VR, Pasqualucci CA, Seeley WW, Spina S, Suemoto CK, Temple S, Kaufer D, Grinberg LT

18F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy.

Molecular neurodegeneration
2025

Alosco ML, Mejía Pérez J, Culhane JE, Shankar R, Nowinski CJ, Bureau S, Mundada N, Smith K, Amuiri A, Asken B, Groh JR, Miner A, Pettway E, Mosaheb S, Tripodis Y, Windon C, Mercier G, Stern RA, Grinberg LT, Soleimani-Meigooni DN, Christian BT, Betthauser TJ, Stein TD, McKee AC, Mathis CA, Abrahamson EE, Ikonomovic MD, Johnson SC, Mez J, La Joie R, Schonhaut D, Rabinovici GD

Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers.

JAMA neurology
2025

VandeVrede L, Cho H, Sanderson-Cimino M, Wekselman F, Cobigo Y, Gorno-Tempini ML, Heuer HW, Kramer JH, Lario Lago A, Leichter D, Ljubenkov P, Miller BL, Perry DC, Rabinovici GD, Rojas JC, Rosen HJ, Saloner R, Staffaroni A, Triana-Baltzer G, Spina S, Seeley WW, Grinberg LT, Kolb HC, La Joie R, Boxer AL

Clinical and neuropathological associations of plasma Aβ42/Aβ40, p-tau217 and neurofilament light in sporadic frontotemporal dementia spectrum disorders.

Alzheimer's & dementia (Amsterdam, Netherlands)
2025

Rajbanshi B, Prufer Q C Araujo I, VandeVrede L, Ljubenkov PA, Staffaroni AM, Heuer HW, Lario Lago A, Ramos EM, Petrucelli L, Gendron T, Dage JL, Seeley WW, Grinberg LT, Spina S, Bateman RJ, Rosen HJ, Boeve BF, Boxer AL, Rojas JC, ALLFTD Consortium

Distinct subcellular localization of tau and alpha-synuclein in lewy body disease.

Acta neuropathologica communications
2025

Fischer DL, Menard M, Abdelaziz OZ, Kanaan NM, Cobbs VG, Kennedy RE, Serrano GE, Beach TG, Volpicelli-Daley LA

Molecular and cellular dynamics of the developing human neocortex.

Nature
2025

Wang L, Wang C, Moriano JA, Chen S, Zuo G, Cebrián-Silla A, Zhang S, Mukhtar T, Wang S, Song M, de Oliveira LG, Bi Q, Augustin JJ, Ge X, Paredes MF, Huang EJ, Alvarez-Buylla A, Duan X, Li J, Kriegstein AR

Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer's disease, and primary age-related tauopathy hippocampi.

Alzheimer's & dementia : the journal of the Alzheimer's Association
2024

Richardson TE, Orr ME, Orr TC, Rohde SK, Ehrenberg AJ, Thorn EL, Christie TD, Flores-Almazan V, Afzal R, De Sanctis C, Maldonado-Díaz C, Hiya S, Canbeldek L, Kulumani Mahadevan LS, Slocum C, Samanamud J, Clare K, Scibetta N, Yokoda RT, Koenigsberg D, Marx GA, Kauffman J, Goldstein A, Selmanovic E, Drummond E, Wisniewski T, White CL, Goate AM, Crary JF, Farrell K, Alosco ML, Mez J, McKee AC, Stein TD, Bieniek KF, Kautz TF, Daoud EV, Walker JM

Hypertension may associate with cerebral small vessel disease and infarcts through the pathway of intracranial atherosclerosis.

Neurobiology of aging
2024

Takahashi MKN, Paradela RS, Grinberg LT, Leite REP, Farias-Itao DS, Paes VR, Braga ME, Naslavsky MS, Zatz M, Jacob-Filho W, Nitrini R, Pasqualucci CA, Suemoto CK

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