Alzheimer's drug lecanemab slows cognitive decline but concerns linger

By Grace Wade on December 01, 2022
The lecanemab group also had substantial decreases to the number of misfolded proteins in the brain called tau tangles. These proteins increased in the control group. “Tau is the abnormal protein in Alzheimer’s disease that has the best correlation with clinical decline,” says Lea Grinberg at the...

Best postdoctoral poster competition award AAIC 2022

By Abhijjit Satpati on September 30, 2022
Grinberg lab's very own Postdoc Abhijit Satpati

Loss of Neurons, Not Lack of Sleep, Makes Alzheimer’s Patients Drowsy Reviving “Awake Neurons” Could Be the Solution to Their Sleepiness, UCSF Study Shows

By Robin Marks on April 04, 2022
The lethargy that many Alzheimer’s patients experience is caused not by a lack of sleep, but rather by the degeneration of a type of neuron that keeps us awake, according to a study that also confirms the tau protein is behind that neurodegeneration. The study’s findings contradict the common...

Ladders Inc.: This very normal habit could be a symptom of Alzheimer’s Disease

By CW Headley on October 27, 2021
This article was updated on August 12, 2021. A report published in the Journal of Alzheimer’s and Dementia, posits that toxic clumps of a protein called tau might be what causes Alzheimer’s disease.

DGIST Ph.D. candidate receiving a degree from DGIST and Maastricht University, Gowoon Son, DGIST

By Kwanghoon Choi on July 12, 2021
Gowoon Son, an Integrated M.S. and Ph.D. student in the department of Brain & Cognitive Sciences, successfully completed the graduate program of Maastricht University in Netherlands to receive Ph.D. from both DGIST and Maastricht University.

Brain Cells Most Vulnerable to Alzheimer’s Disease Identified by Scientists Findings Could Lead to Targeted Treatments to Boost Brain’s Resilience

By Nicholas Weiler on January 11, 2021
A major mystery in Alzheimer’s disease research is why some brain cells succumb to the creeping pathology of the disease years before symptoms first appear, while others seem impervious to the degeneration surrounding them until the disease’s final stages. 

UCSF News: Alzheimer’s Disease Destroys Neurons that Keep Us Awake

By Nicholas Weiler on September 04, 2019
Study Suggests Tau Tangles, Not Amyloid Plaques, Drive Daytime Napping That Precedes Dementia

Mapping the human brain to combat Alzheimer's

By Berkeley Institute for Data Science on July 16, 2018
An article featuring research lead by Grinberg lab post-doctoral fellow Maryana Alegro, PhD for Berkeley's Institute for Data Science (BIDS). To read the full article, see the BIDS webpage.

UCSF Faculty Senate Profile

By Kathryn Sill on February 02, 2018
Profile and video of Prof. Lea Grinberg written and produced by the UCSF Faculty Senate discussing her work as a scientist, and how her life growing up in Brazil has lead to her career as a neuropathologist. Read the full text at the Faculty Senate Website.

UCSF News: Early Alzheimer’s Brain Pathology Linked to Psychiatric Symptoms

By Nicholas Weiler on October 12, 2017
Coverage of Grinberg lab study on the pathological foundations for early neuropsychiatric symptoms in Alzheimer's disease. See the full story at the UCSF News site.