Publications

Clinical Manifestations.

2023

Asken BM, Tanner JA, Soleimani-Meigooni DN, Knudtson MV, Grinberg LT, Miller BL, Kramer JH, Mez JB, Alosco ML, Rabinovici GD

Clinical Manifestations.

2023

Illán-Gala I, Lorca-Puls DL, Miller Z, Rubio-Guerra S, Santos-Santos MA, Lleó A, Grinberg LT, Spina S, Rankin KP, Kramer JH, Rabinovici GD, Boxer AL, Rosen HJ, Perry DC, Miller BL, Seeley WW, Mandelli ML, Tempini MLG

Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum.

2023

Illán-Gala I, Lorca-Puls DL, Tee BL, Ezzes Z, de Leon J, Miller ZA, Rubio-Guerra S, Santos-Santos M, Gómez-Andrés D, Grinberg LT, Spina S, Kramer JH, Wauters LD, Henry ML, Boxer AL, Rosen HJ, Miller BL, Seeley WW, Mandelli ML, Gorno-Tempini ML

Synaptic proteasome is inhibited in Alzheimer's disease models and associates with memory impairment in mice.

2023

Ribeiro FC, Cozachenco D, Heimfarth L, Fortuna JTS, de Freitas GB, de Sousa JM, Alves-Leon SV, Leite REP, Suemoto CK, Grinberg LT, De Felice FG, Lourenco MV, Ferreira ST

Mutant tau and stress lead to downregulation of long noncoding RNA, SNHG8.

2023

Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Eteleeb AM, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM

FTLD targets brain regions expressing recently evolved genes.

2023

Pasquini L, Pereira FL, Seddighi S, Zeng Y, Wei Y, Illán-Gala I, Vatsavayai SC, Friedberg A, Lee AJ, Brown JA, Spina S, Grinberg LT, Sirkis DW, Bonham LW, Yokoyama JS, Boxer AL, Kramer JH, Rosen HJ, Humphrey J, Gitler AD, Miller BL, Pollard KS, Ward ME, Seeley WW

Single-cell analysis of prenatal and postnatal human cortical development.

2023

Velmeshev D, Perez Y, Yan Z, Valencia JE, Castaneda-Castellanos DR, Wang L, Schirmer L, Mayer S, Wick B, Wang S, Nowakowski TJ, Paredes M, Huang EJ, Kriegstein AR

Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.

2023

Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS

Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy.

2023

Walker JM, Orr ME, Orr TC, Thorn EL, Christie TD, Yokoda RT, Vij M, Ehrenberg AJ, Marx GA, McKenzie AT, Kauffman J, Selmanovic E, Wisniewski T, Drummond E, White CL, Crary JF, Farrell K, Kautz TF, Daoud EV, Richardson TE

Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics.

2023

Rexach JE, Cheng Y, Chen L, Polioudakis D, Lin LC, Mitri V, Elkins A, Yin A, Calini D, Kawaguchi R, Ou J, Huang J, Williams C, Robinson J, Gaus SE, Spina S, Lee EB, Grinberg LT, Vinters H, Trojanowski JQ, Seeley WW, Malhotra D, Geschwind DH

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