bioRxiv : the preprint server for biology

Developmental Plasticity and Stromal Co-option Shape a Pituitary Neuroendocrine Tumor Transcriptional Continuum.

Osorio RC, Oh JY, Jung J, Ehrenberg AJ, Saha A, Lad M, Khela H, Brennick N, Giannikopoulos P, Seeley WW, Grinberg LT, Diaz A, Aghi MK

Single-nucleus epigenomic dysregulation unmasks genetic risk-associated neurodegenerative glia states.

Han X, Zhang T, Lee CY, Ravi A, Spina S, Li AN, Grinberg LT, Seeley WW, Huckins LM, Raj T, Brennand KJ, Rexach JE

Extracellular Ca2+-Sensing Receptor (CaSR) Regulates Hypothalamic Function to Control Energy and Skeletal Metabolism in Mice.

Park-Sigal J, Norton M, Tu CL, Cheng Z, Fadahunsi N, Lee H, Kim S, Li A, Grinberg LT, Bewick GA, Murphy KG, Chang W

β-Amyloid Induces Microglial Expression of GPC4 and APOE Leading to Increased Neuronal Tau Pathology and Toxicity.

Holmes BB, Weigel TK, Chung JM, Kaufman SK, Apresa BI, Byrnes JR, Kumru KS, Vaquer-Alicea J, Gupta A, Rose IVL, Zhang Y, Nana AL, Alter D, Grinberg LT, Spina S, Leung KK, Condello C, Kampmann M, Seeley WW, Coutinho-Budd JC, Wells JA

Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1.

Yu D, Jain S, Wangzhou A, De Florencio S, Zhu B, Kim JY, Choi JJ, Paredes MF, Nowakowski TJ, Huang EJ, Piao X

Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease.

Zhu B, Wangzhou A, Yu D, Li T, Schmidt R, De Florencio SL, Chao L, Perez Y, Grinberg LT, Spina S, Ransohoff RM, Kriegstein AR, Seeley WW, Nowakowski T, Piao X

Molecular and cellular dynamics of the developing human neocortex at single-cell resolution.

Wang L, Wang C, Moriano JA, Chen S, Zuo G, Cebrián-Silla A, Zhang S, Mukhtar T, Wang S, Song M, de Oliveira LG, Bi Q, Augustin JJ, Ge X, Paredes MF, Huang EJ, Alvarez-Buylla A, Duan X, Li J, Kriegstein AR

Conservation, alteration, and redistribution of mammalian striatal interneurons.

Corrigan EK, DeBerardine M, Poddar A, Turrero García M, Schmitz MT, Harwell CC, Paredes MF, Krienen FM, Pollen AA

The wake and sleep-modulating neurons of the lateral hypothalamic area demonstrate a differential pattern of degeneration in Alzheimer's disease.

Satpati A, Soloviev AV, Pereira FL, Mladinov M, Larsen E, Leite REP, Suemoto CK, Rodriguez RD, Paes VR, Walsh C, Spina S, Seeley WW, Pasqualucci CA, Filho WJ, Neylan TC, Grinberg LT

Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy.

Leng K, Cadwell CR, Patrick Devine W, Tihan T, Qi Z, Singhal N, Glenn O, Kamiya S, Wiita A, Berger A, Shieh JT, Titus EW, Paredes MF, Upadhyay V

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